High level of uric acid (or medically termed as hyperuricaemia) is described as a condition wherein serum uric acid (SUA) level crosses seven milligrams per deciliter among males or six milligrams per deciliter among ladies largely in their mid-sixties.
It develops because of uric acid surplusage in the blood from breakdown of purines or due to the presence of some ailment/health problem like cancer. Usually, uric acid after dissolution in the blood eventually gains entry into the kidneys which filter wastes and finally its disposal via urination or processing in the intestinal region occurs.
Signs & Symptoms Of High Uric Acid Levels
Symptoms differ across individuals based on how severe the condition is, though several of them might be asymptomatic.
Hyperuricaemia could lead to an excruciating condition, gout which is a form of arthritis resulting from precipitation of spine-like crystalline structures of uric acid in the capillary and joint areas. Inflammation in the joints triggers severe pains, especially in the foot (large toe), hand, knee, ankle, elbow and wrist areas.
Although such pains are experienced unexpectedly, commonly after dusk and dissipating thereafter but the discomfort tends to linger on for protracted periods of time. Flare-ups occur intermittently in a single or several joints at an instant which involve abrupt inception of reddishness, swell up, intense soreness and feeling of warmth that subside by itself in a couple of days.
Uric acid tends to crystallize subsequent to prolonged periods of suffering from gout attacks, typically leading to subcutaneous lump formations. They are termed as tophi and aren’t tender to touch except during attacks, often occurring in the toe, hand, elbow or finger areas.
Symptoms of fever like shivering, body temperature well above 37 degrees Celsius and weariness can arise due to excessive serum accruement of uric acid which is classically linked to pre-existent health conditions.
Cancer sufferers who undergo chemotherapy experience several side-effects inclusive of surfeit uric acid levels along with pyrexia, queasiness, lost craving for food and diarrhea.
Ureteral Obstruction, Stone Formation And/Or Malfunction Of Kidneys
The tubular structure carrying wastes to the urinary bladder from kidneys gets blocked due to elevated uric acid levels causing several discomforting signs and symptoms. They include abnormally low urine production, bloody urine, turbid urine, higher than normal readings of blood pressure, fluid build-up in body, exhaustion and stomach pains.
When uric acid saturates in the bloodstream it leads to the formation of kidney stones due to urate crystallizing in the kidneys. Small-sized stones generally aren’t causal to symptoms but after passage into the tiny ureter tubes could trigger acute pains in any of the organs of the renal system.
Sudden, acute bilateral pain in the individual’s back at the precise location of the kidneys, groin, abdominal or just above the hipbone slightly to the back accompanied by pyrexia, blood in urine and puking.
Acute or chronic renal failure can result due to elevated levels of uric acid as the excretory organs are incapable of extracting toxic matter from the body and expelling it through urination.
In acute renal failure the individual senses chest pains, breathlessness, exhaustion, reduction in urination, swollen upper and/or lower extremity and feeling mentally confused. Muscular cramping, sleeplessness and lost craving for foods are symptoms of chronic renal failure.